Epidemiology and Treatment of Kaposi’s Sarcoma in HIV-1 Infected Individuals in a Poor Resource Setting
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Addressing controversies over Kaposi's sarcoma.
Kaposi’s sarcoma has emerged from being a rarity to being the most important neoplasm in many sub-Saharan countries. Most investigators involved in Kaposi’s sarcoma research now agree that the gammaherpesvirus human herpesvirus 8 (HHV8), also called Kaposi’s sarcoma-associated herpesvirus (KSHV), is central in the pathogenesis of this disease (1,2). Molecular and seroepidemiologic studies (3,4)...
متن کاملAre the Preventive Services For HHV-8 Necessary in HIV Positive Persons in Central Zone of Iran?
Background and Objective: It is presumed that human herpes virus 8 (HHV-8) is the necessary cause of all different forms of Kaposi’s sarcoma which is the most common neoplasm in HIV-infected persons. In this study, we wanted to determine the prevalence of HHV8 infection in all the available Isfahan (Central Iran) HIV positive individuals in comparison with healthy blood donor, and also inves...
متن کاملتعیین شیوع عفونت فعال هرپس ویروس انسانی تیپ 8 و ژنوتیپ آن در افراد مبتلا به ویروس نقص ایمنی انسان
Background and Aim: Considering the lack of information on the occurrence of the epidemic form of Kaposi’s sarcoma (KS) and the high prevalence of human herpesvirus 8 (HHV-8) infection among human immunodeficiency virus (HIV)-infected patients (46%), it was decided to estimate the incidence of KS in this group. Based on the fact that active HHV-8 infection leads to KS development, it is essenti...
متن کاملComparison of Prevalence of Kaposi’s Sarcoma in HHV8 and HHV8 HIV Infected Patients in South-South Nigeria
This study was carried out to see if there are any differences between the prevalence of Kaposi’s sarcoma in HIV infected patients with antibody to Human Herpes Virus 8 (HHV8) or not. Methods: The sera of 180 subjects were evaluated for HIV and HHV8 using double ELISA (Genscreen Ultra HIV Ag-Ab ELISA and JN HIV 1/2 ELISA Kit) for HIV screening and advanced Biotechnology Incorporated ELISA for H...
متن کاملفراوانی نشانه‌های پوستی، نحوه آلودگی و محل ضایعات در بیماران مبتلا به عفونت HIV در استان اصفهان در سال 1385
Background and aim: it has been estimated that 70000-100000 cases of HIV infection exist in Iran. The main route of transmission is intravenous drug (IV) injection. Rapid spread of this disease necessitates its prompt diagnosis. About 90% of HIV infected patients express cutaneous manifestations therefore, recognition of these symptoms may be of help in early diagnosis.Methods: HIV infected pat...
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